Buffalo Homes with Mixed Use Style

Welcome to Buffalo County, Wisconsin, a hidden gem nestled between the rolling hills and pristine rivers of the Driftless Area. Known for its breathtaking landscapes and vibrant community spirit, Buffalo County offers a unique blend of rural charm and modern convenience. With a rich history and a warm, welcoming atmosphere, this county is an ideal place for families, outdoor enthusiasts, and anyone seeking a tranquil lifestyle close to nature.

One of the standout features of Buffalo County is its diverse real estate offerings, particularly homes with mixed-use styles. These innovative properties are perfect for those looking to combine residential living with business opportunities. Imagine waking up in your beautifully designed home and just a few steps away, running your own shop, café, or studio. The flexibility of mixed-use homes allows for a seamless work-life balance, making it easier to pursue your passions while being part of the vibrant local community.

Buffalo County is also home to stunning outdoor recreational activities, with its numerous parks, hiking trails, and waterways. Whether you enjoy fishing, kayaking, or simply taking in the scenic views, there's something for everyone here. The county’s rich agricultural heritage and commitment to sustainability make it an appealing choice for those who value a connection to nature.

Explore the unique charm of Buffalo County and discover the ideal mixed-use home that fits your lifestyle. With its perfect blend of community, convenience, and captivating landscapes, Buffalo County is not just a place to live; it’s a place to thrive.

Newest Buffalo Homes with Mixed Use Style

$219,000

2 Beds ⋅ 2 Baths ⋅ 7063623 MLS

Opportunity awaits in the heart of downtown Nelson. This mixed use property offers a versatile main level commercial space, a spacious upper level apartment, and extensive lower level storage. Positioned along a well traveled downtown corridor that has previously reported traffic counts of approximately 15,000 vehicles per day, the storefront provides excellent visibility for retail, office, service based businesses, or a variety of entrepreneurial ventures. The property also includes ownership of both driveways and an oversized two car garage, offering valuable parking and access flexibility. Upstairs, the residential unit offers an ideal setup for an owner operator looking to live on site, provide employee housing, or generate additional rental income. The apartment features large living spaces filled with natural light, two bedrooms, a full kitchen, two bathrooms, newer windows installed in 2020, and additional flex space that could serve as storage, office space, or a sunroom. Original woodwork adds character throughout, while the layout offers opportunities to update and tailor the space to your vision. The lower level provides substantial storage and utility space, adding even more functionality for business operations. A unique opportunity to establish your business while benefiting from additional residential space in a prime downtown Nelson location near the Mississippi River.

S101 S Main Street, Nelson

Listing courtesy of Re/Max Results.

$214,000

7061302 MLS

Exceptional opportunity to own a well maintained mixed-use property in the heart of downtown Alma along Wisconsin’s scenic Great River Road. This versatile building features retail/commercial space on the main level with excellent storefront visibility in a high-traffic downtown location, along with a spacious upper-level apartment offering Mississippi River views. The upper level includes two generous rooms that provide flexibility for bedroom, office, or additional living space needs, along with a bathroom. Whether you're looking to create comfortable living quarters above your business or generate additional rental income, this property offers versatility to fit a variety of needs. Located near Alma’s popular shops, restaurants, marina access, river attractions, Buena Vista Park, and the Great Alma Fishing Float, this property is well positioned for an owner-occupied business, investment opportunity, or live/work lifestyle in one of the Mississippi River’s most charming historic communities.

117 N Main Street, Alma

Listing courtesy of Re/Max Results.

$395,000

7056657 MLS

Rare opportunity to own one of Wisconsin’s most historic and beloved hospitality destinations. Originally known as the Union House and dating back to the pre-Civil War era, the Historic Alma Hotel is recognized as one of the oldest continually operating restaurants in the state. Located along the scenic Great River Road in Alma, this well-established property features a full-service restaurant, bar, outdoor patio, breakfast area, game room, exterior cooler, and additional storage space with a covered lean-to. A commercial food license for catering creates added income potential. The upper-level hotel accommodations include eight guest rooms, with two offering double beds, two offering queen beds, and four offering full-size beds, along with six shared bathrooms and two private bathrooms. Known for its strong regional reputation and loyal customer base, the property draws both locals and visitors traveling through the Mississippi River region year-round. Recent updates include refinished floors (April 2026), an updated electrical panel (2022), and a fully remodeled commercial kitchen with all equipment replaced within the past four years, with all appliances included. A truly unique opportunity to own a thriving business rich in history, character, and lasting community presence.

201 N Main Street, Alma

Listing courtesy of Re/Max Results.

$94,900

1 Baths ⋅ 7052429 MLS

What was once the German American Bank Building with 2 Bank Vaults (Est. 1906) and later Bautch Insurance (Est. 1947) has now been improved and ready for you to establish this building with your Vision, Service or Big Ideal in mind. New Owners have recently replaced all flooring with LVP, have repainted all services, constructed a new interior wall and added new ceiling tiles which will enable the new owner to hit the ground running! This 1,275 sqft single level building includes a large, open front room, a 1/2 bathroom, a 2nd sink and utility area, 2 secure rooms which each housed 2 massive bank vaults, plus 2 additional, fully finished rooms. Forced air/Central A/C for efficient heating and cooling, beautiful new flooring, paint & ceilings make this space perfect for many purposes. Business, retail, or personal living are all options and with an asking price of under $95,000 - we expect that many prospective Buyers will be interested!

117 S Main Street, Alma

Listing courtesy of Jewson Realty.

$200,000

5 Beds ⋅ 3 Baths ⋅ 7020483 MLS

Mixed-use investment opportunity in downtown Alma, Wisconsin overlooking the Mississippi River. This well-maintained property features a leased commercial storefront on the main level and two residential units, creating a strong income-producing opportunity with leases already in place. The main floor commercial space offers prominent street frontage with large front windows and an open interior currently occupied by a salon tenant (business not included). Residential units offer spacious layouts, full kitchens, and comfortable living areas suited for long-term tenancy. Property has been carefully maintained by current ownership and includes 3-phase electrical service. Upper-level balcony and living spaces capture scenic Mississippi River views, adding to the building’s character and tenant appeal. A strong opportunity for investors seeking a stabilized mixed-use property with established rental income in Alma.

103 S Main Street, Alma

Listing courtesy of Jewson Realty.

Start Your Search

The data relating to real estate for sale on this web site comes in part from the Broker Reciprocity Program of the Regional Multiple Listing Service of Minnesota. Real estate listings held by brokerage firms other this firm are marked with the Broker Reciprocity logo. Information Deemed Reliable But Not Guaranteed. Property locations as displayed on any map are best approximations only and exact locations should be independently verified.

Listing data © 2026 Regional Multiple Listing Service of Minnesota. All rights reserved. By searching, you agree to the EULA.